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Home All anti-MAP3K7IP1 antibodies
Anti-MAP3K7IP1 Antibody
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for MAP3K7IP1 (NM_006116)
OriGene Data
| TAB1 antibody was raised against a synthetic peptide corresponding to 13 amino acids in the center of human TAB1. |
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IgG |
| Human, Mouse |
1ug/ul |
| WB, IF |
ELISA, WB: 0.5 - 2 ug/ml, ICC: 1 ug/ml, IF: 2 ug/ml |
| PBS containing 0.02% sodium azide. |
| Affinity chromatography purified via peptide column (Protein A or G Sepharose) |
Reference Data
| Homo sapiens TGF-beta activated kinase 1/MAP3K7 binding protein 1 (TAB1), transcript variant alpha |
| 3 -Tab1; MAP3K7IP1 |
| NP_006107 |
| TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7 (1), which is known to mediate various intracellular signaling pathways, such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily (2), thus acting as an intermediate in both proliferative and innate and adaptive immune responses (3). This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals (4,5). It has been shown that the C-terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF-beta, demonstrating how this protein can function as a mediator between TGF-beta receptors and TAK1 (6). |
MAPK signaling pathway TGF Beta Signaling Pathway Toll-like receptor signaling pathway |
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis of TAB1 in 3T3 cell lysate with TAB1 antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.
IF Image
Immunocytochemistry of TAB1 in K562 cells with TAB1 antibody at 1 ug/mL.
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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