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Home Antibody All anti-Il1rl1 antibodies

Anti-Il1rl1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306180
  • Rabbit Polyclonal ST2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401271) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for Il1rl1 (NM_003856)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenST2 antibody was raised against a synthetic peptide corresponding to 16 amino acids at the amino-terminus of mouse ST2. This peptide is common to all three known ST2 isoforms.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interleukin 1 receptor-like 1 (IL1RL1), transcript variant 2
Alternative NameDER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1
Database LinkNP_003847
Entrez Gene 9173 Human
Entrez Gene 17082 Mouse
FunctionST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF (3). More recently, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor (TLR) 4 signaling and to maintain endotoxin tolerance (4,5). It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP (6).
Related PathwaySecreted ProteinTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of ST2 in mouse kidney lysate with ST2 antibody at 1 ug/ml in the presence (lane A) or absence (lane B) of 1 ug blocking peptide.
IHC Image
Immunohistochemistry of ST2 in mouse kidney tissue with ST2 antibody at 2 ug/ml.

 

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