OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-BAK1 antibodies

Anti-BAK1 Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306175
  • Rabbit Polyclonal Bak Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400476) , 20ug
100ug 325 3-7 Days
Add to Shopping Cart
WB(1)
IF(1)

OriGene Data

ImmunogenBak antibody was raised against a peptide corresponding to 13 amino acids near the amino-terminus of human Bak.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens BCL2-antagonist/killer 1 (BAK1)
Alternative NameBAK; BAK-LIKE; BCL2L7; CDN1
Database LinkNP_001179
FunctionApoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria (4,5). It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking bak and bax show decreased apoptotic capability (6,7).
Related Pathway
Apoptosis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Bak in L1210 cell lysates with Bak antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of Bak in L1210 cells with Bak antibody at 2 ug/mL.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title