Invalid object name 'antibody_LocusMapping'. Anti-BCL2 Antibody, - OriGene
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Anti-BCL2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306172
  • Rabbit Polyclonal Bcl-2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424602) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for BCL2 (NM_000633)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenBcl-2 antibody was raised against a peptide corresponding to 14 amino acids near the middle of human Bcl-2.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 4 ug/ml, ICC: 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens B-cell CLL/lymphoma 2 (BCL2), transcript variant alpha
Alternative NameBcl-2; PPP1R50
Database LinkNP_000624
FunctionApoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). Bcl-2 is the founding member of a family of over 20 proteins that are critical regulators of apoptosis (reviewed in 2 and 3). These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-2 is an inner mitochondrial membrane protein that inhibits apoptosis (4). It is thought to act by interacting with pro-apoptotic Bcl-2 family members such as Bak and Bad (5 for review). Overexpression of Bcl-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer (4,6).
Related Pathway
Apoptosis
Focal Adhesion

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Bcl-2 in A-20 cell lysates with Bcl-2 antibody at (A) 1, (B) 2, and (C) 4 ug/mL.
IF Image
Immunocytochemistry of Bcl-2 in A20 cells with Bcl-2 antibody at 2 ug/mL.

 

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