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Home Antibody All anti-TICAM2 antibodies

Anti-TICAM2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306163
  • Rabbit Polyclonal TIRP Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402870) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for TICAM2 (NM_021649)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTIRP antibody was raised against a peptide corresponding to amino acids near the C-terminus of human TIRP.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens toll-like receptor adaptor molecule 2 (TICAM2)
Alternative NameMyD88-4; TICAM-2; TIRAP3; TIRP; TRAM
Database LinkNP_067681
FunctionTIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB (5). Expression of TIRP appears to be essential for TLR4 signalling (6).
Related Pathway
Toll-like receptor signaling pathway

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WB Image
Western blot analysis of TIRP in human (A), mouse (B), and rat (C) kidney cell lysates with TIRP antibody (C2) at 1 ug/ml.
IHC Image
Immunohistochemical staining of Daudi cells using SARM antibody at 2 ug/ml.

 

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