Home Antibody All anti-SARM1 antibodies
Also for SARM1 (NM_015077)
|SARM antibody was raised against a peptide corresponding to amino acids near the C-terminus of human SARM.|
||ELISA, WB: 0.5 - 2 ug/ml, ICC: 2 ug/ml, IF: 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Ion exchange chromatography purified
|Homo sapiens sterile alpha and TIR motif containing 1 (SARM1)|
|MyD88-5; SAMD2; SARM|
Entrez Gene 23098 Human
Entrez Gene 237868 Mouse
|Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-kappaB, and ultimately the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interluekin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.|
|Druggable Genome |
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis of SARM in Daudi cell lysates with SARM antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.
Figure from citation: Western Blot of SARM1 protein level by using anti-SARM1 antibody in retinal protein extracts of Thy1-YFP mice. View Citation
Immunocytochemistry staining of Daudi cells using SARM antibody at 2 ug/mL.