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Home Antibody All anti-SARM1 antibodies

Anti-SARM1 Antibody

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Specifications Citations (1) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306162
  • Rabbit Polyclonal SARM Antibody
100ug 325 In Stock
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WB(1)
IF(1)
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Also for SARM1 (NM_015077)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenSARM antibody was raised against a peptide corresponding to amino acids near the C-terminus of human SARM.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 0.5 - 2 ug/ml, ICC: 2 ug/ml, IF: 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens sterile alpha and TIR motif containing 1 (SARM1)
Alternative NameMyD88-5; SAMD2; SARM
Database LinkNP_055892
FunctionToll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-kappaB, and ultimately the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interluekin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of SARM in Daudi cell lysates with SARM antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.
IF Image
Immunocytochemistry staining of Daudi cells using SARM antibody at 2 ug/mL.

 

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