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Home Antibody All anti-LY96 antibodies

Anti-LY96 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306161
  • Rabbit Polyclonal MD-2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC414593) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for LY96 (NM_015364)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenMD-2 antibody was raised against a peptide corresponding to amino acids near the middle region of human MD-2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens lymphocyte antigen 96 (LY96), transcript variant 1
Alternative NameESOP-1; ly-96; MD-2; MD2
Database LinkNP_056179
FunctionMD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS (5,6). The specificity of this response is determined by the species of MD-2; e.g., human MD-2 can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4 (7).
Related Pathway
Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of MD-2 in mouse spleen cell lysate with MD-2 antibody at 1 ug/ml.
IHC Image
Immunohistochemical staining of rat spleen cells using MD-2 antibody at 2 ug/ml.

 

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