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Home Antibody All anti-TLR8 antibodies

Anti-TLR8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306159
  • Rabbit Polyclonal TLR8 Antibody
100ug 325 In Stock
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WB(1)
IF(1)

OriGene Data

ImmunogenTLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 0.5 - 2 ug/ml, ICC: 2 ug/ml, IF: 10 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens toll-like receptor 8 (TLR8), transcript variant 2
Alternative NameCD288
Database LinkNP_619542
Entrez Gene 51311 Human
Entrez Gene 170744 Mouse
FunctionToll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). Like TLR7, TLR8 is localized to endosomal or lysosomal compartments (6) and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA (7). Human but not murine TLR8 confers responsiveness to the antiviral compound R-848 (8).
Related Pathway
Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TLR8 in Daudi cell lysates with TLR8 antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.
IF Image
Immunocytochemistry of TLR8 in Daudi cells with TLR8 antibody at 2 ug/mL.

 

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