Home Antibody All anti-Tlr11 antibodies
Also for Tlr11 (NM_205819)
|TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy-terminus of mouse TLR11.|
||ELISA, WB: 0.5 - 1 ug/ml, ICC: 2 ug/ml, IF: 10 ug/ml
|PBS containing 0.02% sodium azide.|
|Ion exchange chromatography purified (Protein A or G Sepharose)
|Mus musculus toll-like receptor 11 (Tlr11)|
|Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).|
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Western blot analysis of TLR11 in RAW264.7 cell lysates with TLR11 antibody at (A) 0.5 and (B) 1 ug/mL.
Immunocytochemical staining of RAW264.7 cells using TLR11 antibody at 2 ug/mL.