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Home Antibody All anti-TICAM1 antibodies

Anti-TICAM1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306137 Rabbit Polyclonal TRIF Antibody 100ug $325 3-7 Days
LC403651 TICAM1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenTRIF antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRIF.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2 - 4 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens toll-like receptor adaptor molecule 1 (TICAM1), transcript variant 1
Alternative NameTRIF, PRVTIRB, TICAM-1, MGC35334;MGC35334; PRVTIRB; TICAM-1; TRIF; TIR domain containing adaptor inducing interferon-beta; TIR domain-containing adaptor molecule 1; toll-like receptor adaptor molecule 1
Database LinkNP_055076
Entrez Gene 148022 Human
FunctionTRIF is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TRIF, along with other molecules such as TIRP, TIRAP, and MyD88, serves as an adaptor protein to several of the TLR molecules. Following activation of TLR3 and TLR4, TRIF engages the kinase TBK1 and allows its subsequent activation of the interferon regulatory factor (IRF)-3 (5). TRIF is also involved in the activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-?B (6).
Related PathwayDruggable Genome Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of TRIF in human lung cell lysates with TRIF antibody at (A) 2 and (B) 4 ug/ml.
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Immunohistochemistry of TRIF in human lung tissue with TRIF antibody at 10 ug/ml.
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