Home Antibody All anti-TLR2 antibodies
Also for TLR2 (NM_003264)
|TLR2 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TLR2.|
||Lot dependent; please refer to CoA along with shipment
||IHC: 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Ion exchange chromatography purified
|Homo sapiens toll-like receptor 2 (TLR2)|
Entrez Gene 7097 Human
Entrez Gene 24088 Mouse
|Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kappaB (4-6). TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer can recognize a variety of bacterial and mycoplasma lipoproteins respectively (reviewed in 7).|
|TransmembraneDruggable Genome Toll-like receptor signaling pathway|
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Western blot analysis of TLR2 in A20 cell lysates with TLR2 antibody at 1 ug/ml in the presence (A) and absence (B) of its blocking peptide.
Immunohistochemical staining of human spleen cells using TLR2 antibody at 2 ug/ml.