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Home Antibody All anti-AICDA antibodies

Anti-AICDA Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306117 Rabbit Polyclonal AID Antibody 100ug $325 In Stock
LC412399 AICDA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IF(1)

OriGene Data

ImmunogenAID antibody was raised against a peptide corresponding to 14 amino acids near the carboxy-terminus of human AID.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 2 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens activation-induced cytidine deaminase (AICDA)
Alternative NameAID; ARP2; CDA2; HEL-S-284; HIGM2
Database LinkNP_065712
Entrez Gene 57379 Human
Entrez Gene 11628 Mouse
FunctionActivation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines (1). It is necessary for somatic hypermutation and class switch recombination in B cells (2), but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms (2,3). Although it is structurally and functionally similar to the APOBEC proteins (reviewed in 4), it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G (5).
Related PathwayDruggable Genome Primary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of AID in Ramos whole cell lysate with AID antibody at 2 ug/mL in either the (A) absence or (B) presence of blocking peptide.
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Immunocytochemistry of AID in Ramos cells with Ramos antibody at 10 ug/mL.
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