Home Antibody All anti-TTC5 antibodies
Also for TTC5 (NM_138376)
|TTC5 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TTC5.|
||WB: 0.5 - 1 ug/ml; IHC: 10ug/ml
|PBS containing 0.02% sodium azide.|
|Immunoaffinity purified IgG
|Homo sapiens tetratricopeptide repeat domain 5 (TTC5)|
Entrez Gene 91875 Human
Entrez Gene 219022 Mouse
|Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats (1). Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 (2) and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5 (3), suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.|
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Western blot analysis of TTC5 in RAW264.7 cell lysate with TTC5 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Immunohistochemistry of TTC5 in mouse brain tissue with TTC5 antibody at 10 ug/ml.