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Home Antibody All anti-TTC5 antibodies

Anti-TTC5 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306112 Rabbit Polyclonal TTC5 Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenTTC5 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TTC5.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.5 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Immunoaffinity purified IgG

Reference Data

Target NameHomo sapiens tetratricopeptide repeat domain 5 (TTC5)
Alternative NameStrap
Database LinkNP_612385
Entrez Gene 91875 Human
Entrez Gene 219022 Mouse
FunctionTetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats (1). Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 (2) and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5 (3), suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TTC5 in RAW264.7 cell lysate with TTC5 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.

IHC Image
Immunohistochemistry of TTC5 in mouse brain tissue with TTC5 antibody at 10 ug/ml.

IF Image
Immunofluorescence of TTC5 in Mouse Brain cells with TTC5 antibody at 20 ug/mL.


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