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Home Antibody All anti-TTC5 antibodies

Anti-TTC5 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306112
  • Rabbit Polyclonal TTC5 Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenTTC5 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TTC5.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml; IHC: 10ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Immunoaffinity purified IgG

Reference Data

Target NameHomo sapiens tetratricopeptide repeat domain 5 (TTC5)
Alternative NameStrap
Database LinkNP_612385
FunctionTetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats (1). Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 (2) and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5 (3), suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
Related Pathway

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WB Image
Western blot analysis of TTC5 in RAW264.7 cell lysate with TTC5 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
IHC Image
Immunohistochemistry of TTC5 in mouse brain tissue with TTC5 antibody at 10 ug/ml.

 

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