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Home Antibody All anti-IL27RA antibodies

Anti-IL27RA Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306081 Rabbit Polyclonal TCCR Antibody 100ug $325 3-7 Days
LC417709 IL27RA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for IL27RA (NM_004843)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenTCCR antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human TCCR precursor This sequence is identical to that of mouse TCCR.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target Nameinterleukin 27 receptor subunit alpha
Alternative NameCRL1|IL-27RA|IL27R|TCCR|WSX1|zcytor1
Database LinkNP_004834
Entrez Gene 9466 Human
FunctionUpon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned (1,2). It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1 (1,2). TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a . TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Western blot analysis of TCCR expression in human spleen tissue lysate with TCCR antibody at 1 ug /ml.
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IHC Image
mmunohistochemistry of TCCR in human spleen tissue with TCCR antibody at 5 ug/ml.
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IF Image
Immunofluorescence of TCCR in Human Spleen cells with TCCR antibody at 20 ug/mL.
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