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Home Antibody All anti-IL21R antibodies

Anti-IL21R Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306078
  • Rabbit Polyclonal IL-21 Receptor Antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenIL-21 receptor antibody was raised against a synthetic peptide corresponding to amino acids 20 to 32 of human IL-21 receptor precursor.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interleukin 21 receptor (IL21R), transcript variant 1
Alternative NameCD360; NILR
Database LinkNP_068570
Entrez Gene 50615 Human
Entrez Gene 60504 Mouse
Entrez Gene 308977 Rat
FunctionA novel cytokine related to IL2 and IL15 was recently identified and designated IL-21 . The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IL-21 receptor expression in human Raji cell lysate with IL-21 receptor antibody at 1 µg /ml.

 

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