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Home Antibody All anti-IKBKG antibodies

Anti-IKBKG Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306055
  • Rabbit Polyclonal IKK gamma Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400446) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for IKBKG (NM_001099856)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenIKK gamma antibody was raised against a peptide corresponding to amino acids 400 to 416 of human IKK gamma, which are identical to those of mouse homologue.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 2
Alternative NameAMCBX1; FIP-3; FIP3; Fip3p; IKK-gamma; IP; IP1; IP2; IPD2; NEMO; ZC2HC9
Database LinkNP_001093326
FunctionNuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappaB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-kappaB activity. The IkB kinase (IKKalpha and IKKbeta) phosphorylates IkB and mediates NF-kappaB activation. A novel molecule in the IKK complex was recently identified and termed IKKgamma/NEMO/FIP3/IKKAP1 (1-5). IKKg interacts with IKKbeta and is required for the activation of IKK complex and NF-kappaB by LPS, PMA, TNF, and IL-1 stimulation (1-4). FIP3 was also shown to bind to RIP and NIK and to mediate TNF-induced NF-kappaB activation (3).
Related Pathway
Apoptosis
MAPK signaling pathway
Toll-like receptor signaling pathway

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WB Image
Western blot analysis of IKK gamma in HeLa whole cell lysate with IKK gamma antibody at 1 ug/mL.
IF Image
Immunocytochemistry of IKK gamma in HeLa cells with IKK gamma antibody at 5 ug/mL.

 

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