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Home Antibody All anti-DAPK2 antibodies

Anti-DAPK2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306051
  • Rabbit Polyclonal DAPK2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402315) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for DAPK2 (NM_014326)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDAPK2 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DAPK2. The sequence of this antigenic peptide is identical to the corresponding amino acids of mouse origin (1,2).
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens death-associated protein kinase 2 (DAPK2)
Alternative NameDRP-1; DRP1
Database LinkNP_055141
Entrez Gene 23604 Human
Entrez Gene 13143 Mouse
Entrez Gene 300799 Rat
FunctionApoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as RIP and DAP kinase, are mediators of apoptosis. DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain. Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation. DAPK mediates IFNg induced apoptosis. A novel DAP kinase-related protein was recently identified and designated DAPK2 and DRP-1 (1, 2). Ectopicly expressed DAPK2 induced apoptosis in various types of cells (1,2). DAPK has high sequence homology to ZIP kinase and DRAK1/2, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. The messenger RNA of DAPK2 is expressed in multiple human tissues (1).
Related PathwayProtein KinaseDruggable Genome Pathways in cancerBladder cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of DAPK2 in A431 (H), mouse spleen (M), and rat kidney (R) lysates with DAPK2 antibody at 1 ug/ml.
IHC Image
Immunohistochemistry of DAPK2 in mouse spleen cells with DAPK2 antibody at 2 ug/ml.

 

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