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Home Antibody All anti-Birc5 antibodies

Anti-Birc5 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306027
  • Rabbit Polyclonal mSurvivin Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenSurvivin antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of mouse Survivin.
Clone Name IsotypeIgG
Species ReactivityMouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameMus musculus baculoviral IAP repeat-containing 5 (Birc5), transcript variant 1
Alternative NameAAC-11; Api4; survivin40; TIAP
Database LinkNP_033819
FunctionApoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP (1-3). Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas (1,3).
Related Pathway

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WB Image
Western blot analysis of survivin in mouse spleen tissue lysate with survivin antibody at 1 ug/ml.
IHC Image
Immunohistochemistry of Survivin in mouse spleen cells with Survivin antibody at 10 ug/ml.

 

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