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Home Antibody All anti-STK17B antibodies

Anti-STK17B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306007
  • Rabbit Polyclonal DRAK2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401355) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for STK17B (NM_004226)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDRAK2 antibody was raised against a peptide corresponding to amino acids 351 to 365 of human DRAK2.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB, ICC: 10 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens serine/threonine kinase 17b (STK17B)
Alternative NameDRAK2
Database LinkNP_004217
Entrez Gene 9262 Human
FunctionApoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases) (1). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues (1).
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of DRAK2 in Jurkat (1,3) and Raji (2,4) cell lysate in the absence (1,2) or presence (3,4) of blocking peptide with DRAK2 antibody at 1:500 dilution.
IF Image
Immunocytochemistry of DRAK2 in Jurkat cells with DRAK2 antibody at 10 ug/mL.

 

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