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Home Antibody All anti-BAG4 antibodies

Anti-BAG4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306005
  • Rabbit Polyclonal SODD Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417692) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for BAG4 (NM_004874)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSODD antibody was raised against a peptide corresponding to amino acids near the amino terminus of human SODD.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 0.5 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Antibody is DEAE purified

Reference Data

Target NameHomo sapiens BCL2-associated athanogene 4 (BAG4), transcript variant 1
Alternative NameBAG-4; SODD
Database LinkNP_004865
Entrez Gene 9530 Human
Entrez Gene 67384 Mouse
Entrez Gene 361167 Rat
FunctionApoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domains (1). SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of SODD in HeLa (1,3) and THP-1 (2,4) whole cell lysates in the absence (1,2) or presence (3,4) of blocking peptide (Catalog no. 2143P) with SODD antibody at 1:500 dilution.
IF Image
Immunocytochemistry of SODD in HeLa cells with SODD antibody at 5 ug/mL.

 

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