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Home Antibody All anti-IL1RAP antibodies

Anti-IL1RAP Antibody


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SKU Description Amount Price Availability*  
TA306001 Rabbit Polyclonal IL-1RAcP Antibody 100ug $325 In Stock
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OriGene Data

ImmunogenIL-1RAcP antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of IL-1RAcP, which differs from the sequence of mouse origin by three amino acids.
Clone Name IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 0.5 ug/mL, ICC: 5 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interleukin 1 receptor accessory protein (IL1RAP), transcript variant 3
Alternative NameC3orf13; IL-1RAcP; IL1R3
Database LinkNP_001161400
Entrez Gene 3556 Human
FunctionThe pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I(IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1).IL-1 RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kappaB inducing kinae (NIK) and of NF-kappaB, recruites to the IL-1R complex through IL-1 RAcP(2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP(3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.
Related PathwaySecreted ProteinTransmembraneDruggable Genome Cytokine-cytokine receptor interactionApoptosis

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WB Image
Western blot analysis of IL-1RAcP in HeLa whole cell lysate with IL-1RAcP antibody at 1:500 dilution.

IF Image
Immunocytochemistry of IL-1RAcP in HeLa cells with IL-1RAcP antibody at 5 ug/mL.


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