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Home Antibody All anti-CCR8 antibodies

Anti-CCR8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305990
  • Rabbit Polyclonal CCR8 Antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenCCR8 antibody was raised against a peptide corresponding to amino acids 183 to 201 of human CCR8, which locate in the second extracellular loop.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1:500 - 1:1000
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens chemokine (C-C motif) receptor 8 (CCR8)
Alternative NameCC-CKR-8; CCR-8; CDw198; CKRL1; CMKBR8; CMKBRL2; CY6; GPRCY6; TER1
Database LinkNP_005192
Entrez Gene 1237 Human
FunctionCCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
Related PathwayGPCRTransmembraneDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CCR8 in human spleen lysate with CCR8 antibody at 1:500 dilution.

 

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