Home Antibody All anti-CX3CR1 antibodies
Also for CX3CR1 (NM_001171171)
|CX3CR1 antibody was raised against a peptide corresponding to amino acids 2 to 21 of human CX3CR1. The sequence differs from those of mouse and rat CX3CR1 by four amino acids (3,4).|
|Human, Mouse, Rat
||WB: 1:500 - 1:2000
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column (Protein A or G Sepharose)
|Homo sapiens chemokine (C-X3-C motif) receptor 1 (CX3CR1), transcript variant 2|
|CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28|
|CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2).|
Cytokine-cytokine receptor interaction
Signaling by GPCR
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis of CX3CR1 in human spleen lysate with CX3CR1 antibody in the absence (lane 1) or presence of blocking peptide (lane 2).
Immunohistochemical staining of human heart tissue using CX3CR1 antibody at 2 ug/ml