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Home Antibody All anti-Cidea antibodies

Anti-Cidea Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305987
  • Rabbit Polyclonal CIDE-A Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenCIDE-A antibody was raised against a peptide corresponding to amino acids 200 to 214 of mouse CIDE-A.
Clone Name IsotypeIgG
Species ReactivityMouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500 - 1:1000
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameMus musculus cell death-inducing DNA fragmentation factor, alpha subunit-like effector A (Cidea)
Alternative NameAW212747
Database LinkNP_031728
Entrez Gene 12683 Mouse
FunctionApoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (1). CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (1,2). Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-A is expressed in many tissues.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CIDE-A in mouse heart tissue lysate with CIDE-A antibody at 1:500 dilution.
IHC Image
Immunohistochemistry of CIDE-A in mouse heart tissue with CIDE-A antibody at 5 ug/ml.

 

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