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Home Antibody All anti-BCL2L11 antibodies

Anti-BCL2L11 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA305980 Rabbit Polyclonal Bim Antibody 100ug $325 3-7 Days
LC416580 BCL2L11 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenBim antibody was raised against a peptide corresponding to amino acids near the center of human Bim. The sequence is identical to that of mouse and differs from that of rat by one amino acid .
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 6
Alternative NameBAM; BIM; BOD
Database LinkNP_006529
Entrez Gene 10018 Human
Entrez Gene 12125 Mouse
Entrez Gene 64547 Rat
FunctionMembers in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat (1,2). Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines (1,2).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of Bim in K562 (K) and A549 (A) whole cell lysates with Bim antibody at 1 ug/ml.
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Immunohistochemistry of Bim in human skin cancer cells with Bim antibody at 20 ug/ml.
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