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Home Antibody All anti-TNFRSF25 antibodies

Anti-TNFRSF25 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305961
  • Rabbit Polyclonal DR3 Antibody
100ug $325 In Stock
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WB(1)
IF(1)
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Also for TNFRSF25 (NM_001039664)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenDR3 antibody was raised against a peptide corresponding to amino acids in extracellular domain (ED) of human DR3 precusor.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Antibody is DEAE purified

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 25 (TNFRSF25), transcript variant 12
Alternative NameAPO-3; DDR3; DR3; LARD; TNFRSF12; TR3; TRAMP; WSL-1; WSL-LR
Database LinkNP_001034753
FunctionApoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kappaB activation.
Related Pathway
Apoptosis
Cytokine-cytokine receptor interaction

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WB Image
Western blot analysis of DR3 in Jurkat total cell lysate with DR3 antibody at 1:1000 dilution.
IF Image
Immunocytochemistry of DR3 in Jurkat cells with DR3 antibody at 10 ug/mL.

 

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