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Home Antibody All anti-TNFSF10 antibodies

Anti-TNFSF10 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305942
  • Rabbit Polyclonal Trail Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418411) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for TNFSF10 (NM_003810)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTRAIL antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human TRAIL.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), transcript variant 1
Alternative NameApo-2L; APO2L; CD253; TL2; TRAIL
Database LinkNP_003801
FunctionApoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (for TNF-related apoptosis-inducing ligand) and Apo-2L (for Apo-2 ligand)1,TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL3-6. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kappaB activation in many tissues and cells.
Related Pathway
Apoptosis
Cytokine-cytokine receptor interaction

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WB Image
Western blot analysis of TRAIL in HeLa cell lysate containing 10, 2.5, or 1 ng of recombinant protein containing extracellular domain of TRAIL with TRAIL antibody at 1 ug/ml.
IHC Image
Immunohistochemistry of TRAIL in human brain tissue with TRAIL antibody at 20 ug/ml.

 

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