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Home Antibody All anti-STAT1 antibodies

Anti-STAT1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA305937 Rabbit Polyclonal STAT1 alpha Antibody 100ug $325 3-7 Days
LC429341 STAT1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IF(1)
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Also for STAT1 (NM_007315)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenSTAT1 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human STAT1 alpha The sequences differ from the murine corresponding sequences by four amino acids.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1:1000 - 1:2000, ICC: 10 ug/ml, IP: 2 - 4 ug/sample
BufferPBS containing 0.02% sodium azide.
Purification Antibody is DEAE purified

Reference Data

Target NameHomo sapiens signal transducer and activator of transcription 1, 91kDa (STAT1), transcript variant alpha
Alternative NameCANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
Database LinkNP_009330
Entrez Gene 6772 Human
Entrez Gene 20846 Mouse
Entrez Gene 25124 Rat
FunctionSTATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, and Stat6), Stat1, Stat3, Stat5alpha, and Stat5beta have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-alpha, IFN-beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1). STAT1 has two forms, the 91 kDa STAT1alpha and the 84 kDa STAT1beta which are encoded by the same gene with splicing variant.
Related PathwayTranscription FactorsDruggable Genome Chemokine signaling pathwayToll-like receptor signaling pathwayJak-STAT signaling pathwayPathways in cancerPancreatic cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of STAT1 alpha in whole cell lysates from HeLa (H), Jurkat (J), A431 (A), K562 (K), and NIH3T3 (N) cells, with STAT1a antibody at 1 ug/mL.
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Immunocytochemistry of STAT1 alpha in HeLa cells with STAT1 alpha antibody at 10 ug/mL.
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