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Home Antibody All anti-LIG1 antibodies

Anti-LIG1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA305925 Goat Anti-LIG1 / DNA ligase I Antibody 100ug $325 3-7 Days
LC424847 LIG1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-RVREDKQPEQATTS, from the internal region (near C-Terminus) of the protein sequence according to NP_000225.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.1-0.3ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens ligase I, DNA, ATP-dependent (LIG1), transcript variant 1
Alternative NameMGC117397; MGC130025
Database LinkNP_000225
Entrez Gene 3978 Human
Entrez Gene 81513 Rat
FunctionLIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq].
Related PathwayDruggable Genome DNA replicationBase excision repairNucleotide excision repairMismatch repair

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA305925 (0.1ug/ml) staining of HeLa nuclear lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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