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Home Antibody All anti-CAV3 antibodies

Anti-CAV3 Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA305791 Goat Anti-CAV3 Antibody 100ug $325 In Stock
LC420058 CAV3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(2)
IHC(1)
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OriGene Data

ImmunogenPeptide with sequence EHTDLEAQIVKDIH-C, from the N Terminus of the protein sequence according to NP_203123.1.
Clone Name IsotypeGoat IgG
Species ReactivityTested: Human, Mouse, Rat, Pig. Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Pig Concentration0.5mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.1-0.3 µg/ml. IHC: 3-5 µg/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens caveolin 3 (CAV3), transcript variant 2
Alternative NameLGMD1C; LQT9; VIP-21; VIP21
Database LinkNP_001225
Entrez Gene 859 Human
Entrez Gene 12391 Mouse
Entrez Gene 29161 Rat
Entrez Gene 484671 Dog
FunctionThis gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. [provided by RefSeq].
Related PathwayTransmembraneDruggable Genome Focal adhesion

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
TA305791 (0.1 ug/ml) staining of Pig Skeletal Muscle (A) and Heart (B) lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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WB Image
TA305791 (0.3 ug/ml) staining of Mouse (A) and Rat (B) Heart lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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IHC Image
TA305791 (3.8 ug/ml) staining of paraffin embedded Human Skeletal Muscle. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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