Home Antibody All anti-Ramp1 antibodies
Also for Ramp1 (NM_005855)
|Peptide with sequence C-DYQSKRTEGIV, from the C-Terminus of the protein sequence according to NP_058590.1; NP_848488.2.|
|Test: Rat. Expected from seq similarity: Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
|0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
|Homo sapiens receptor (G protein-coupled) activity modifying protein 1 (RAMP1)|
|receptor (calcitonin) activity modifying protein 1; receptor-activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1|
Entrez Gene 10267 Human
Entrez Gene 51801 Mouse
Entrez Gene 58965 Rat
|The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq]. |
|TransmembraneDruggable Genome Vascular smooth muscle contraction|
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TA305755 (0.3ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.