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Home Antibody All anti-CHMP5 antibodies

Anti-CHMP5 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA305742 Goat Anti-CHMP5 Antibody 100ug $325 3-7 Days
LC414005 CHMP5 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-NKDGVLVDEFGLPQ, from the C Terminus of the protein sequence according to NP_057494.3.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens charged multivesicular body protein 5 (CHMP5), transcript variant 1
Alternative NameC9orf83; CGI-34; HSPC177; PNAS-2; SNF7DC2; Vps60
Database LinkNP_057494
Entrez Gene 51510 Human
Entrez Gene 76959 Mouse
Entrez Gene 297995 Rat
FunctionCHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM].
Related Pathway Endocytosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA305742 (xug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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