Home Antibody All anti-RNF34 antibodies
Also for RNF34 (NM_194271)
|Peptide with sequence KAGATSMWASCC, from the N Terminus of the protein sequence according to NP_919247.1; NP_079402.2.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow
|0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
|Homo sapiens ring finger protein 34, E3 ubiquitin protein ligase (RNF34), transcript variant 1|
|CARP-1; CARP1; hRFI; RFI; RIF; RIFF|
Entrez Gene 80196 Human
Entrez Gene 80751 Mouse
Entrez Gene 282845 Rat
Entrez Gene 477470 Dog
|The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]. |
|Druggable Genome |
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TA305687 (3.8ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.