Home Antibody All anti-XPNPEP1 antibodies
Also for XPNPEP1 (NM_001167604)
|Peptide with sequence C-LIRETQPISKQH, from the C-Terminus of the protein sequence according to NP_065116.2; NP_001161076.1.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat.Cow, Pig, Dog
|0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
|Homo sapiens X-prolyl aminopeptidase (aminopeptidase P) 1, soluble (XPNPEP1), transcript variant 2|
|APP1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1|
Entrez Gene 7511 Human
Entrez Gene 170750 Mouse
Entrez Gene 170751 Rat
Entrez Gene 486880 Dog
|X-prolyl aminopeptidase (EC 188.8.131.52) is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline, it has been suggested that X-prolyl aminopeptidase is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases. Deficiency of X-prolyl aminopeptidase results in excretion of large amounts of imino-oligopeptides in urine (Blau et al., 1988 [PubMed 3141711]).[supplied by OMIM]. |
|ProteaseDruggable Genome |
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TA305684 (0.3ug/ml) staining of Human Pancreas lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.