Home Antibody All anti-KPNA6 antibodies
Also for KPNA6 (NM_012316)
|Peptide with sequence C-STTGESVITREMVE, from the internal of the protein sequence according to NP_036448.1.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow
|0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
|Homo sapiens karyopherin alpha 6 (importin alpha 7) (KPNA6)|
Entrez Gene 23633 Human
Entrez Gene 16650 Mouse
Entrez Gene 362607 Rat
Entrez Gene 487314 Dog
|Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. |
|Druggable Genome |
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TA305673 (0.1ug/ml) staining of Human Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.