Home Antibody All anti-TMPRSS2 antibodies
Also for TMPRSS2 (NM_001135099)
|Peptide with sequence C-TDWIYRQMRADG, from the internal region of the protein sequence according to NP_005647.2.|
||0.5~1.0 mg/ml (Lot Dependent)
|0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
|Homo sapiens transmembrane protease, serine 2 (TMPRSS2), transcript variant 1|
|This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
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TA305658 (0.1ug/ml) staining of Human Pancreas Lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.