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Home Antibody All anti-PIK3C2A antibodies

Anti-PIK3C2A Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA305643 Goat Anti-PIK3C2A Antibody 100ug $325 3-7 Days
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IHC(1)

OriGene Data

ImmunogenPeptide with sequence C-TVKWYQLTAATYL, from the C Terminus of the protein sequence according to NP_002636.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Dog Concentration0.5 mg/ml
Guaranteed Application *IHC Suggested DilutionsIHC: 5-10ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target Namephosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Alternative NameCPK|PI3-K-C2(ALPHA)|PI3-K-C2A|PI3K-C2-alpha|PI3K-C2alpha
Database LinkNP_002636
Entrez Gene 5286 Human
Entrez Gene 18704 Mouse
Entrez Gene 485399 Dog
FunctionThe protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq].
Related PathwayDruggable Genome Inositol phosphate metabolismMetabolic pathwaysPhosphatidylinositol signaling system

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


IHC Image
TA305643 (5ug/ml) staining of paraffin embedded Human Heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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