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Home Antibody All anti-KCNJ1 antibodies

Anti-KCNJ1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305615
  • Goat Anti-KCNJ1 / ROMK Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400081) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-DQININFVVDAGNEN , from the internal region of the protein sequence according to NP_000211.1; NP_722448.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens potassium inwardly-rectifying channel, subfamily J, member 1 (KCNJ1), transcript variant 1
Alternative NameKIR1.1; ROMK; ROMK1
Database LinkNP_000211
Entrez Gene 3758 Human
Entrez Gene 56379 Mouse
Entrez Gene 24521 Rat
FunctionPotassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayIon Channels: PotassiumTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA305615 (1ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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