Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566.
[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 2 (GABBR2)
Synonyms:
GABABR2; GPR51; GPRC3B; HG20; HRIHFB2099
Immunogen
A phospho specific peptide corresponding to residues surrounding serine 893 of human GABA(B) R2 was used as an immunogen. This antibody detects GABA(B) R2 phosphorylated on serine 893.
Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase. See GABBR1 (MIM 603540) for additional background information on GABA-B receptors.[supplied by OMIM].
Related Pathway
Signaling by GPCR
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Western blot analysis on human brain lysates using anti-Phospho-GABA(B) R2 (pS893) RabMAb (TA303868), 1:1000 dilution. Cells were either (A) untreated (B) treated with AP.
