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Anti-GABBR2 PHOSPHO Antibody EP2318Y
Also for GABBR2 (NM_005458)
|A phospho specific peptide corresponding to residues surrounding serine 893 of human GABA(B) R2 was used as an immunogen. This antibody detects GABA(B) R2 phosphorylated on serine 893.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:500 -1000; IHC: 1:100; ICC: 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 2 (GABBR2)|
|GABABR2; GPR51; GPRC3B; HG20; HRIHFB2099|
|B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase. See GABBR1 (MIM 603540) for additional background information on GABA-B receptors.[supplied by OMIM]. |
Signaling by GPCR
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Western blot - GABA B Receptor 2 (phospho S893) antibody [EP2318Y]; All lanes : Anti-GABA B Receptor 2 (phospho S893) antibody [EP2318Y] at 1/1000 dilution.Lane 1 : Human brain lysate - untreated.Lane 2 : Human brain lysate - treated with AP.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled Goat anti-Rabbit antibody at 1/2000 dilution.Observed band size : 106 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GABA B Receptor 2 (phospho S893) antibody [EP2318Y]; Immunohistochemical analysis of phosphorylated GABA B Receptor 2 expression on paraffin-embedded Human brain tissue using 1/100 ab68426. Heat mediated antigen retrieval was performed, and an HRP-conjugated polymerized secondary antibody was used.