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Home Antibody All anti-FADD antibodies

Anti-FADD Antibody EP887Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303862
  • Rabbit monoclonal antibody against FADD (N-term)(EP887Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401265) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for FADD (NM_003824)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-term of human FADD was used as immunogen.
Clone NameEP887Y IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500; IHC: 1:100 - 250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Rat

Reference Data

Target NameHomo sapiens Fas (TNFRSF6)-associated via death domain (FADD)
Alternative NameGIG3; MORT1
Database LinkNP_003815
FunctionThe protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq].
Related Pathway
Apoptosis
Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - FADD antibody [EP887Y]; Anti-FADD antibody [EP887Y] at 1/500 dilution + Jurkat cell lysate at 10 ug.Secondary.HRP-labelled goat anti-rabbit.Predicted band size : 23 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - FADD antibody [EP887Y]; Immunohistochemical analysis of paraffin-embedded human lung tissue using TA303862 at a dilution of 1/100-1/250.

 

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