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Home Antibody All anti-HDAC3 antibodies

Anti-HDAC3 Antibody EP462Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303857
  • Rabbit monoclonal antibody against Histone Deacetylase 3 (N-term) (EP462Y )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401280) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for HDAC3 (NM_003883)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of Histone deacetylase 3 was used as an immunogen.
Clone NameEP462Y IsotypeIgG
Species ReactivityHuman, Mouse ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:2000; IHC-P: 1:100 - 1:250; ICC: 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens histone deacetylase 3 (HDAC3)
Alternative NameHD3; RPD3; RPD3-2
Database LinkNP_003874
FunctionHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-HDAC3 [EP462Y] antibody; Anti-HDAC3 [EP462Y] antibody at 1/2000 dilution + HeLa cell lysate at 10 µg.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 49 kDa.Observed band size : 49 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HDAC3 [EP462Y] antibody; TA303857, at a 1/100-1/250 dilution, staining human HDAC3 in breast carcinoma, by Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue.

 

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