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Anti-TSC2 Antibody EP1107Y
Also for TSC2 (NM_000548)
|A synthetic peptide corresponding to residues of human Tuberin was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:100000; IP: 1:70; FC: 1:70; IHC-P: Use at an assay dependent dilution
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Does not react with Mouse, Rat
|Homo sapiens tuberous sclerosis 2 (TSC2), transcript variant 1|
|LAM; PPP1R160; TSC4|
Entrez Gene 7249 Human
|Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]. |
|Druggable Genome p53 signaling pathwaymTOR signaling pathwayInsulin signaling pathway|
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Western blot - Tuberin antibody [EP1107Y]; Anti-Tuberin antibody [EP1107Y] at 1/100000 dilution + SH-SY5Y cell lysate at 10 ug.Secondary.HRP-labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 201 kDa.Observed band size : ~200 kDa .
Immunohistochemistry (Paraffin-embedded sections) - Tuberin antibody [EP1107Y]; Immunohistochemical analysis of paraffin-embedded human adenocarcinoma of uterus using TA303845 at a dilution of 1/100-1/250.