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Home Antibody All anti-MMP11 antibodies

Anti-MMP11 Antibody EP1259Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303837
  • Rabbit monoclonal antibody against MMP-11 (EP1259Y )
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human MMP-11 was used as an immunogen.
Clone NameEP1259Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:500; IHC-P: Use at an assay dependent dilution
Predicted MW Explanation 55 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens matrix metallopeptidase 11 (stromelysin 3) (MMP11)
Alternative NameSL-3; ST3; STMY3
Database LinkNP_005931
Entrez Gene 4320 Human
Entrez Gene 17385 Mouse
Entrez Gene 25481 Rat
FunctionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq].
Related PathwayProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - MMP11 antibody [EP1259Y]; Anti-MMP11 antibody [EP1259Y] at 1/500 dilution + MCF-7 cell lysate at 10 ug.Secondary.Goat anti-Rabbit HRP labeled. at 1/2000 dilution.Predicted band size : 55 kDa.Observed band size : 55 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - MMP11 antibody [EP1259Y]; Ab52904 (1:100) staining human MMP11 in human breast carcinoma tissue by immunohistochemistry using paraffin embedded tissue.
IF Image
Immunocytochemistry/ Immunofluorescence - MMP11 antibody [EP1259Y]; Immunofluorescent staining of MCF7 cells using TA303837 (1:100).

 

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