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Anti-MMP11 Antibody EP1259Y
Also for MMP11 (NM_005940)
|A synthetic peptide corresponding to residues near the C-terminus of human MMP-11 was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||ICC/IF: 1:100 - 1:250; WB: 1:500; IHC-P: Use at an assay dependent dilution
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens matrix metallopeptidase 11 (stromelysin 3) (MMP11)|
|SL-3; ST3; STMY3|
|Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq]. |
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Western blot - MMP11 antibody [EP1259Y]; Anti-MMP11 antibody [EP1259Y] at 1/500 dilution + MCF-7 cell lysate at 10 µg.Secondary.Goat anti-Rabbit HRP labeled. at 1/2000 dilution.Predicted band size : 55 kDa.Observed band size : 55 kDa.
Immunohistochemistry (Paraffin-embedded sections) - MMP11 antibody [EP1259Y]; Ab52904 (1:100) staining human MMP11 in human breast carcinoma tissue by immunohistochemistry using paraffin embedded tissue.
Immunocytochemistry/ Immunofluorescence - MMP11 antibody [EP1259Y]; Immunofluorescent staining of MCF7 cells using TA303837 (1:100).