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Anti-EZR Antibody EP2122Y


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SKU Description Amount Price Availability*  
TA303834 Rabbit monoclonal antibody against Ezrin/Radixin/Moesin (EP2122Y ) 100ul $325 In Stock
LC401164 EZR HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues surrounding Thr566 (Ezrin 81 kDa) Thr564 (Radixin 81 kDa) and Thr558 (Moesin 75 kDa) of human Ezrin, Radixin and Moesin was used as an immunogen. This antibody will detect all 3 proteins.
Clone NameEP2122Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *IHC, IF Suggested DilutionsWB: 1:1000; IHC: 1:100 -250; ICC: 1:250 -500; IP: 1:40
Predicted MW Explanation 69 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens ezrin (EZR), transcript variant 1
Alternative NameCVIL; CVL; HEL-S-105; VIL2
Database LinkNP_003370
Entrez Gene 7430 Human
Entrez Gene 22350 Mouse
Entrez Gene 54319 Rat
FunctionThe cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Leukocyte transendothelial migrationRegulation of actin cytoskeletonPathogenic Escherichia coli infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Ezrin / Radixin / Moesin antibody [EP2122Y]; Immunohistochemical analysis of paraffin-embedded human breast adenocarcinoma, using TA303834, at 1/100 dilution
Immunocytochemistry/ Immunofluorescence - Ezrin / Radixin / Moesin antibody [EP2122Y]; Immunofluorescent staining of HeLa cells using TA303834, at 1/250 dilution


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