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Home Antibody All anti-PRKCB antibodies

Anti-PRKCB Antibody Y125


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303830 Rabbit monoclonal antibody against PKCßII (Y125) 100ul $325 3-7 Days
LC419133 PRKCB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for PRKCB (NM_002738)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near C-terminus of human PKC beta-II was used as immunogen. The antibody does not cross-react with human PKC beta-I. Predicted to cross-react with mouse and bovine PKC beta, rat and pig PKC beta-II, based on s
Clone NameY125 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application * Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: Use at an assay dependent dilution; ICC/IF: 1:250 - 1:500; FC: 1:50; IP: 1:60
Predicted MW Explanation 77 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Protein A purified

Reference Data

Target NameHomo sapiens protein kinase C beta (PRKCB), transcript variant 2
Alternative NamePKC-beta; PKCB; PRKCB1; PRKCB2
Database LinkNP_002729
Entrez Gene 5579 Human
Entrez Gene 18751 Mouse
Entrez Gene 25023 Rat
FunctionProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayErbB signaling pathwayCalcium signaling pathwayChemokine signaling pathwayPhosphatidylinositol signaling systemVascular smooth muscle contractionMore Pathways >>

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