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Anti-PRKCB Antibody Y125

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

IF(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues near C-terminus of human PKC beta-II was used as immunogen. The antibody does not cross-react with human PKC beta-I. Predicted to cross-react with mouse and bovine PKC beta, rat and pig PKC beta-II, based on s
Clone Name	Y125	Isotype	Rabbit IgG
Species Reactivity	Human, Mouse, Rat	Concentration
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB: 1:500; IHC: 1:100-250; ICC: 1:250-500; FC: 1:50; IP: 1:60
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens protein kinase C, beta (PRKCB), transcript variant 2
Alternative Name	PKC-beta; PKCB; PRKCB1; PRKCB2
Database Link	NP_002729
Function	Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].
Related Pathway	EGFR1 Signaling Pathway Focal Adhesion Hemostasis MAPK signaling pathway Melanogenesis TGF Beta Signaling Pathway Wnt Signaling Pathway

Related Lysate from OriGene • Transient overexpression lysate of protein kinase C, beta (PRKCB), transcript variant 2 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • PRKCB - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • PRKCB - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Prkcb1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • PRKCB - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Prkcb1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens protein kinase C, beta (PRKCB), transcript variant 2 as transfection-ready DNA • Lenti ORF clone of Human protein kinase C, beta (PRKCB), transcript variant 2, mGFP tagged • Lenti ORF clone of Human protein kinase C, beta (PRKCB), transcript variant 2 , Myc-DDK-tagged • GFP-tagged ORF clone of Homo sapiens protein kinase C, beta (PRKCB), transcript variant 2 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens protein kinase C, beta (PRKCB), transcript variant 2 as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens protein kinase C, beta (PRKCB), transcript variant 2 as transfection-ready DNA • Kinase deficient mutant (K371M) of Homo sapiens protein kinase C, beta (PRKCB), transcript variant 2 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)