OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-TIRAP antibodies

Anti-TIRAP Antibody EP1231Y

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303801
  • Rabbit monoclonal antibody against TIRAP (EP1231Y )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC422104) , 20ug Explanation
100ul 325 3-7 Days
Add to Shopping Cart
spacer
WB(1)
IHC(1)
spacer
Also for TIRAP (NM_001039661)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human TIRAP was used as an immunogen. This antibody detects 3 different isoforms of TIRAP.
Clone NameEP1231Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000; IHC: 1:100 - 250
Predicted MW Explanation 24-30 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), transcript variant 3
Alternative NameBACTS1; Mal; MyD88-2; wyatt
Database LinkNP_001034750
Entrez Gene 114609 Human
Entrez Gene 117149 Mouse
Entrez Gene 680127 Rat
FunctionThe innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq].
Related PathwayDruggable Genome Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - TIRAP antibody [EP1231Y]; Anti-TIRAP antibody [EP1231Y] at 1/1000 dilution + HeLa cell lysate at 10 ug.Predicted band size : 24-30 kDa.Observed band size : 30 kDa .Additional bands at : 24 kDa,27 kDa. We are unsure as to the identity of these extra bands.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - TIRAP antibody [EP1231Y]; Immunohistochemical staining of TIRAP in paraffin embedded human liver tissue using TA303801 at 1/100 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title