OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-DIABLO antibodies

Anti-DIABLO Antibody Y12

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303797
  • Rabbit monoclonal antibody against Smac/Diablo(E12)
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(1)
IF(1)
spacer
Also for DIABLO (NM_138929)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to C-terminal residues human Smac/DIABLO was used as immunogen.
Clone NameY12 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000; IHC-P: Use at an assay dependent dilution; ICC: 1:10; IP: 1:10 - 1:80; FC: 1:10 - 1:50; ICC/IF: Use at an assay dependent concentration
Predicted MW Explanation 27 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Protein A purified

Reference Data

Target NameHomo sapiens diablo, IAP-binding mitochondrial protein (DIABLO), nuclear gene encoding mitochondrial protein, transcript variant 3
Alternative NameDFNA64; DIABLO-S; SMAC; SMAC3
Database LinkNP_620307
Entrez Gene 56616 Human
Entrez Gene 66593 Mouse
Entrez Gene 288753 Rat
FunctionThis gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq].
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Smac / Diablo antibody [Y12]; Anti-Smac / Diablo antibody [Y12] at 1/1000 dilution + Jurkat cell lysate.Predicted band size : 27 kDa.Observed band size : 21 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Smac / Diablo antibody [Y12]; TA303797, at a 1/10 dilution, staining human Smac/Diablo in skin cancer tissue by Immunohistochemistry, Paraffin embedded tissue
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-Smac / Diablo antibody [Y12]; Immunofluorescence analysis of IMR32 cells, staining Smac / Diablo with TA303797. Cells were fixed with 4% paraformaldehyde before incubating with primary antibody. An AlexaFluor?-conjugated anti-rabbit IgG was used as the secondary antibody.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title