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Anti-PARD3 Antibody EP310Y
Also for PARD3 (NM_019619)
|A synthetic peptide corresponding to residues near the C-terminus of human ASIP was used as immunogen. This antibody is predicted to detect isoforms 2-7 based on sequence analysis.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:500; FC: 1:20
|Does not react with Mouse, Rat. Is unsuitable for ICC,IHC or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for ICC,IHC or IP.
|Homo sapiens par-3 family cell polarity regulator (PARD3), transcript variant 1|
|ASIP; Baz; PAR3; PAR3alpha; PARD-3; PARD3A; PPP1R118; SE2-5L16; SE2-5LT1; SE2-5T2|
Entrez Gene 56288 Human
|PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins (GAPs; see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048)-interactive binding (CRIB) domain.[supplied by OMIM]. |
| Chemokine signaling pathwayNeuroactive ligand-receptor interactionEndocytosisAdherens junctionTight junction|
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Western blot - PAR3 antibody [EP310Y]; All lanes : Anti-PARD3 antibody [EP310Y] at 1/500 dilution.Lane 1 : LNCap.Lane 2 : HeLa.Lane 3 : A431.Lane 4 : MCF-7.Lysates/proteins at 10 ug per lane.Predicted band size : 150 kDa.Observed band size : 150 kDa.