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Home Antibody All anti-SIRT1 antibodies

Anti-SIRT1 PHOSPHO Antibody EPR2849Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303785
  • Rabbit monoclonal antibody against Sir2/SIRT1 Phospho (pS47) (EPR2849Y ) (phospho-specific)
100ul 325 3-7 Days
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WB(1)
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Also for SIRT1 (NM_012238)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA phospho specific peptide corresponding to residues surrounding serine 47 of human Sir2/SIRT1 was used as an immunogen. This antibody detects Sir2/SIRT1 phosphorylated on ser 47
Clone NameEPR2849Y IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 -2000; IHC: 1:250 -500; ICC: 1:100 -250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens sirtuin 1 (SIRT1), transcript variant 1
Alternative NameSIR2L1
Database LinkNP_036370
FunctionThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Related Pathway

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WB Image
Western blot - SIRT1 (phospho S47) antibody [EPR2849Y]; All lanes : Anti-SIRT1 (phospho S47) antibody [EPR2849Y] at 1/2000 dilution.Lane 1 : 293 cell lysate.Lane 2 : 293 cell lysate treated with LP.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 82 kDa.Observed band size : 82 kDa.

 

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