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Home Antibody All anti-VAV3 antibodies

Anti-VAV3 Antibody EP1130Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303772
  • Rabbit monoclonal antibody against Vav3 (Pan)(EP1130Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC421571) , 20ug Explanation
100ul 325 In Stock
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WB(1)
FC(1)
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Also for VAV3 (NM_001079874)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-term of human Vav3 was used as an immunogen.
Clone NameEP1130Y IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:50; FC: 1:40; ICC/IF: Use at an assay dependent concentration
BufferDoes not react with Rat. Is unsuitable for IHC-P.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IHC-P.

Reference Data

Target NameHomo sapiens vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2
Alternative NameFLJ40431
Database LinkNP_001073343
Entrez Gene 10451 Human
Entrez Gene 57257 Mouse
FunctionThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Chemokine signaling pathwayFocal adhesionNatural killer cell mediated cytotoxicityT cell receptor signaling pathwayB cell receptor signaling pathwayFc epsilon RI signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - VAV3 antibody [EP1130Y]; Anti-VAV3 antibody [EP1130Y] at 1/100000 dilution + Jurkat cell lysate at 10 ug.Secondary.HRP-labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 98 kDa.Observed band size : ~98 kDa .
FC Image
Flow Cytometry - VAV3 antibody [EP1130Y]; Flow cytometric analysis of permeabilized Jurkat cells using TA303772 (red) or a rabbit IgG (negative) (green).

 

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