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Anti-VAV3 Antibody EP1130Y
Also for VAV3 (NM_001079874)
|A synthetic peptide corresponding to residues near the C-term of human Vav3 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:50; FC: 1:40; ICC/IF: Use at an assay dependent concentration
|Does not react with Rat. Is unsuitable for IHC-P.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for IHC-P.
|Homo sapiens vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2|
|This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]. |
EGFR1 Signaling Pathway
Signaling by GPCR
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Western blot - VAV3 antibody [EP1130Y]; Anti-VAV3 antibody [EP1130Y] at 1/100000 dilution + Jurkat cell lysate at 10 µg.Secondary.HRP-labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 98 kDa.Observed band size : ~98 kDa .
Flow Cytometry - VAV3 antibody [EP1130Y]; Flow cytometric analysis of permeabilized Jurkat cells using ab52938 (red) or a rabbit IgG (negative) (green).