Anti-VAV3 Antibody, EP1130Y

Also for VAV3 (NM_001079874)

Gene Name	Homo sapiens vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2
Synonyms:	FLJ40431
Immunogen	A synthetic peptide corresponding to residues near the C-term of human Vav3 was used as an immunogen.
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Clone Name	EP1130Y	Isotype	Rabbit IgG
Species Reactivity	Human, Mouse	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, FC	Suggested Dilutions	WB: 1:100,000; FC: 1:40; IP: 1:50
Background	This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq].
Related Pathway	EGFR1 Signaling Pathway Focal Adhesion Hemostasis Signaling by GPCR

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WB Image

Western blot analysis on Jurket cell lysate using anti-Vav3 RabMAb (TA303772), dilution 1:100,000

FC Image

Flow cytometric analysis of permeabilized Jurkat cells using anti-VAV3 pan RabMAb (red) (TA303772) or a rabbit IgG (negative) (green).

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Anti-VAV3 Antibody EP1130Y

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